| Player | From | Fee | Date | |
|---|---|---|---|---|
 | Diego Carlos | Sevilla | €31,000,000 | 01/07/2022 |
| Phillipe Coutinho | Barcelona | €20,000,000 | 01/07/2022 |
 | Robin Olsen | Roma | €3,500,000 | 01/07/2022 |
 | Boubacar Kamara | Marseille | Free | 01/07/2022 |
| Ludwig Augustinsson | Sevilla | Loan Fee €500,000 | 11/07/2022 |
 | Leander Dendoncker | Wolverhampton | €15,000,000 | 01/09/2022 |
 | Jan Bednarek | Southampton | Loan | 01/09/2022 |
 | Viljami Sinisalo | Burton Albion | End of Loan | 02/01/2023 |
 | Álex Moreno | Real Betis | €13,500,000 | 11/01/2023 |
 | Jhon Durán | Chicago Fire | €16,600,000 | 16/01/2023 |
 | Bertrand Traoré | Basaksehir | End of Loan | 31/01/2023 |
 | Cameron Archer | Middlesborough | End of Loan | 31/05/2023 |
 | Marvelous Nakamba | Luton | End of Loan | 31/05/2023 |
| Tim Iroegbunam | QPR | End of Loan | 31/05/2023 |
| Keinan Davis | Watford | End of Loan | 31/05/2023 |
| Kortney Hause | Watford | End of Loan | 31/05/2023 |
| Jaden Philogene-Bidace | Cardiff | End of Loan | 31/05/2023 |
| Player | To | Fee | Date | |
|---|---|---|---|---|
| Matt Targett | Newcastle | €17,500,000 | 01/07/2022 |
 | Lovre Kalinic | Hajduk Split | Free | 01/07/2022 |
| Dominic Revan | Barnet | Free | 01/07/2022 |
 | Mahmoud Trezeguet | Trabzonspor | €4,000,000 | 04/07/2022 |
 | Conor Hourihane | Derby | Free | 06/07/2022 |
| Finn Azaz | Plymouth | Loan | 11/07/2022 |
| Viljami Sinisalo | Burton Albion | Loan | 11/07/2022 |
| Louis Barry | MK Dons | Loan | 12/07/2022 |
| Wesley | Levante | Loan | 24/07/2022 |
| Jaden Philogene-Bidace | Cardiff | Loan | 26/07/2022 |
| Carney Chukwuemeka | Chelsea | €18,000,000 | 02/08/2022 |
| Aaron Ramsey | Norwich | Loan | 05/08/2022 |
| Kaine Kesler-Hayden | Huddersfield | Loan | 12/08/2022 |
| Keinan Davis | Watford | Loan | 13/08/2022 |
| Bertrand Traoré | Basaksehir | Loan | 22/08/2022 |
| Kortney Hause | Watford | Loan | 22/08/2022 |
| Ben Chrisene | Kilmarnock | Loan | 25/08/2022 |
 | Anwar El Ghazi | PSV Eindhoven | Loan | 31/08/2022 |
| Tim Iroegbunam | QPR | Loan | 01/09/2022 |
| Caleb Chukwuemeka | Crawley Town | Loan | 01/09/2022 |
| Cameron Archer | Middlesborough | Loan | 06/01/2023 |
| Frédéric Guilbert | Strasbourg | Free | 13/01/2023 |
| Danny Ings | West Ham | €12,000,000 | 20/01/2023 |
| Morgan Sansom | Strasbourg | Loan | 23/01/2023 |
| Louis Barry | Salford | Loan | 30/01/2023 |
| Lamar Bogarde | Bristol Rovers | Loan | 31/01/2023 |
| Indiana Vassilev | St. Louis City | Free | 31/01/2023 |
| Marvelous Nakamba | Luton | Loan | 31/01/2023 |
| Aaron Ramsey | Middlesborough | Loan | 31/01/2023 |